Alli Weight Loss Supplement – Effective for women over 50?

Alli Weight Loss Supplement Review

How effective is Alli Weight Loss Supplement for women over 50? Alli is meant for those over 18 years old. We will be looking at those women over 50 who have taken Alli and how effective it is for them.Alli Weight Loss Supplement

ALLI Weight Loss Supplement’s active ingredient is Orlistat. Orlistat is also marketed under the name of Xenical as a prescription medication for obese patients.

“XENICAL is intended for patients with a BMI of greater than or equal to 30 kg/m2 or a BMI of greater than or equal to 27 kg/m2 in the presence of other risk factors such as Alli Weight Loss supplement is Xenical in US as a perscription and is double the strengthhypertension, diabetes, or high cholesterol.”

In this article, we will be looking at Orlistat as an over the counter weight loss supplement marketed under the name of ALLI. As an OTC weight loss supplement, Alli is not as strong as the prescribed “Xenical” (120 mg vs 60 mg).

Alli is Manufactured and distributed by GlaxcoSmithKline

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Alli Weight Loss Supplement – The Only FDA approved over the counter weight loss aid

On February 7, 2007, the US Food and Drug Administration approved the request that

Alli Weight Loss Supplement

Orlistat can be sold over the counter as a weight loss aid. Alli became available in the US in June 2007 as 60 mg capsules, 1/2 the dose of the prescription medication Orlistat.

As the only FDA approved weight loss diet pill for those over 18, Alli has been sold in stores and pharmacies for years now. The reviews are mostly positive that it does, in fact, facilitate weight loss.

Alli Weight Loss Supplement Blocks Fat

Decreased fat absorption into your system means fewer calories are absorbed. Fat has more calories per gram than protein or carbohydrates. A gram of fat has 9 calories versus 4 per gram of protein or carbohydrate.

Alli is claimed to block about 25% of the fat you eat from getting absorbed into your system.  It blocks an enzyme that breaks down fat. Alli is only minimally absorbed into your bloodstream and the stated claim is that there are no direct effects on the heart and nervous systems. This means no heart racing or mood swings.

Alli Weight Loss Supplement Features and Characteristics

Orlistat is the active ingredient in Alli. As an OTC weight loss supplement, Alli can help increase weight loss if a low-fat diet is followed. It can help you lose weight 50 percent more than with diet and exercise alone. However, Alli should be taken with a meal with the fat content of no more than 15 mg.


Alli Weight Loss Supplement Chart to see if you are a candidate


  • The only FDA-approved Over the counter diet pill
  • Blocks absorption of about 25 percent of ingested fat
  • Comes in 2 sizes – 60 counts and 120 counts
  • Orlistat has been the subject of over 100 clinical trials
  • Meant for those over 18 with a BMI of 25 or more
  • No direct effect on metabolism or nervous system
  • Does not elevate blood pressure or cause mood swings

“To determine if Alli (orlistat 60 mg) capsules are right for you, find your height on the chart. You may consider starting with Alli (orlistat 60 mg) if your weight is the same or more than the weight shown for your height.”

Alli Weight Loss Supplement Side Effects –

The most common side effect of Orlistat is Steatorrhea (Oily, loose stools) especially in the first few weeks of starting Alli diet pills. Other Side effects include:

  • Flatulence
  • Intestinal gas with discharge
  • Oily discharge on undergarments
  • diarrhea
  • Incontinence of stool
  • Urgency of Bowel Movements

In order to manage these side effects stick closely to the guidelines. Be careful not to eat more than 15 gms of fat at each meal. Stick to 3 meals per day plus one snack.

The fact that one of the side effects is oily stool frequent stools helps patients not want to eat fat. In this way,  taking Alli has a behavior modification aspect to it.

Guidelines for taking Alli –

  1. Take Alli with meals containing about 15 mg. of fat content
  2. Eat 3 meals per day plus one snack
  3. Take no more than 3 capsules dailyAlli Weight Loss Supplement guidelines
  4. Make sure each meal contains no more than 30 percent calories from fat
  5. Drink plenty of water during the day
  6. Take a Multi-vitamin at bedtime (Orlistat can block fat-soluble vitamins A, E, K, and D)

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 Orlistat may have beneficial effects on Cardiovascular System

Orlistat is a Lipase inhibitor. Lipase is an enzyme that is secreted by the Pancreas and helps digest fats. When lipase is not present, your body will eliminate the fat that is not digested.

There have been more than 100 clinical trials and it was found that Orlistat can help lower cholesterol and blood pressure and also lower risks of Type II Diabetes.

Orlistat works locally in the intestines and is only minimally absorbed by the body. In long-term clinical trials, Orlistat was well tolerated by Diabetic and Non-Diabetic patients.

Alli Weight Loss Supplement Precautions and Interactions

There are certain precautions to heed if you decide to take Alli. Talk to your Doctor or Pharmacist before taking Alli if you have any of these conditions:

  • Chronic Malabsorption Syndrome
  • Gall Bladder problem
  • Underactive Thyroid
  • Kidney Stones
  • Eating Disorders such as Anorexia or Bulimia
  • HIV Infection
  • Seizure disorder

Do not take Alli if you are pregnant or breastfeeding. Talk to your Doctor or Pharmacist if you are taking prescription drugs as there could be interactions with Alli.

Here are some medications that are known to interact with Alli:

  • Blood Thinners
  • HIV Medications
  • Anti-seizure Medications

Alli Customer Reviews and Scores

Alli has an overall 4/5 star rating on Amazon. There are mixed reviews on Amazon for Alli. It works for some and doesn’t work for others. Some hated the oily stools Alli causes.

Alli has been on the market as OTC weight loss supplement since 2007 and has been taken by many. There are lots and lots of reviews of those it has helped. Many of these are women over 50. However, there are some who claim that Alli did not help them at all.

In The Journal of Obesity, the research shows that Orlistat does, in fact, help with weight loss. However, there are some problems and it can explain why it works for some and does not work for others:

There remain, however, two main problems with orlistat as a treatment for obesity. First, although evidence indicates that it can improve weight-loss outcomes, these improvements are not always substantial and there is much variability with many patients showing no improvements at all. Second, research also indicates high attrition rates with patients not adhering to their medication due to the unpleasant side effects and many stoppings taking the drug entirely or using it selectively according to the content of their diet.”

After reading a lot of reviews, some who have taken Alli claim that when it first came out that it worked much better than now. However, there are a lot of reviews of those who say it helped them lose significant amounts of weight. You can read the reviews here.

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Alli Weight Loss Aid Pros and Cons


  • Help you lose 50% more weight than with diet and exercise alone
  • May improve your Blood Pressure
  • May improve your Cholesterol
  • May lower your risk for Diabetes


  • Causes oily frequent stools
  • May cause diarrhea
  • Only for those over 18 and with BMI of 25 or more
  • Several drug interactions
  • May not work as good for some
  • Must take a Multi-Vitamin at Bedtime

Bottom Line on Alli Weight Loss Pill

Alli is an over the counter medication that is half the dose of the prescription Orlistat. It is the only Over the Counter Weight Loss Pill approved by the FDA. There are over 100 Clinical Trials with positive weight loss outcomes. Alli has helped countless people who are overweight and obese lose a lot of weight.

Alli does not seem to work for everyone. It may be because of not following the guidelines or the unpleasant side effects.

If you are thinking about taking Alli, make sure you look at the chart above. If your BMI is not 25 or more, there are other supplements that could help you.

Have you tried Alli? I would love to hear your review of the product. Please leave any questions or comments below.

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This article has 4 Comments

  1. Alli sounds like a great product for people who are overweight and struggle with dieting. I have always loved the fat on meat. I know it is not good for me but I am weak when it comes to resisting it. Alli would be a great help to me but would it remove all the harmful effects of eating fat? Also as it is sold over the counter I wondered if there isn’t the risk of people with an eating disorder taking it when they don’t need it?

    1. Hi Margaret,

      Thanks for your comment. You are not alone with your struggle with dieting. The obesity epidemic especially in the US is staggering and only getting worse. Alli is said to block about 25% of the fat you eat. It only works properly if you eat less fat and calories. In that way Alli would help with the harmful effects of eating fat.

      Yes it is sold over the counter and is contraindicated for anyone with an eating disorder. It also has drug interactions and other indications to heed. There is always a risk of someone disregarding the precautions if they so chose. 

      However, used the right way and with heeding all the precautions, Alli may help overweight people reduce the size of their waist and in turn be more healthy and with less cardiovascular and diabetes risks and live longer and healthier lives.

  2. Great post on Alli. I was thinking about trying it out as I still have a few hard to loose pounds that I am trying to get rid of; however, after reading your post it sounds like I do not fit the criteria to use it according to your weight chart. I am so glad I read you post as I may have jumped into it blindly.

    I always seem to gain around the center as well, and would really like to find something that would help get rid of it. I have heard that people have a lot of luck with the Ketogenic diet. Do you have any insight on Keto? Could it help me loose these last few pounds?

    1. Hi Dena,
      Thanks so much for your comment. If Alli is not for you and you only need to lose a little around the middle, you could try the Ketogenic diet. However, I think it is better to get on a diet like the DASH diet and with a few lifestyle changes and adding a little exercise, you could easily trim your middle effectively. I know a lot of people love the Keto diet and it does work also. Good Luck and let me know how you are doing with it.

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